The U.S. Department of Energy (DOE) has announced new collaboration agreements with 24 organizations to support the Genesis Mission, a national initiative aimed at using artificial intelligence (AI) to accelerate scientific discovery, strengthen national security, and drive innovation in energy.
The announcement follows President Trump’s Executive Order on Removing Barriers to American Leadership In Artificial Intelligence and aligns with the America’s AI Action Plan introduced earlier this year. The plan seeks to promote innovation, reduce reliance on foreign technology, and enhance the capabilities of the American scientific community.
A White House meeting was held today that included industry representatives, U.S. Secretary of Energy Chris Wright, DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil, and Michael Kratsios, Director of the White House Office of Science and Technology Policy. The event marked the start of public-private partnerships focused on developing scalable AI infrastructure for science and ensuring broad access to its benefits.
“Today’s announcement of 24 new research partnerships is only the beginning, as we deliver on President Trump’s mandate to bring the entire scientific community, including companies, universities, non-profits, and Federal agencies, into the Genesis Mission,” said Assistant to the President and OSTP Director Michael Kratsios. “Harnessing cutting-edge AI for science will dramatically increase the productivity of American scientists and researchers. The Genesis Mission will help America’s scientists automate experiment design, accelerate simulations, and generate predictive models that will lead to breakthroughs in energy, manufacturing, drug discovery, and beyond.”
“Thanks to President Trump’s leadership, the Genesis Mission will be transformative for our country, uniting industry, academia, and our National Labs to deliver powerful and impactful scientific discovery and innovation,” said DOE Under Secretary for Science and Genesis Mission Director Dr. Darío Gil. “These agreements help advance President Trump’s Executive Order to build the national AI platform for scientific discovery and uplift the entire U.S. R&D ecosystem.”
The organizations signing memorandums of understanding (MOUs) have either responded to a DOE request for information or are already engaged in projects related to the Genesis Mission through DOE or its National Laboratories. Any products developed under this mission are intended to be compatible across different technological architectures.
Participating organizations include Accenture; AMD; Anthropic; Armada; Amazon Web Services; Cerebras; CoreWeave; Dell; DrivenData; Google; Groq; Hewlett Packard Enterprise; IBM; Intel; Microsoft; NVIDIA; OpenAI; Oracle; Periodic Labs; Palantir; Project Prometheus; Radical AI; xAI; XPRIZE.
DOE intends to continue expanding its network by inviting more private sector partners as well as academic institutions and philanthropic groups. Requests for Information (RFIs) remain open: “Partnerships for Transformational Artificial Intelligence Models” until January 14th 2026 and “Transformational AI Capabilities for National Security” until January 23rd 2026.
Further details about the Genesis Mission can be found at www.genesis.energy.gov.



